科氏狐猴（Propithecus coquereli）身上的皮肤癣菌病（须癣毛癣菌）

Dermatophytosis (Trichophyton mentagrophytes) in a Coquerel's sifaka (Propithecus coquereli).

作者信息

Phair Kristen, Larsen R Scott, Wack Raymund

机构信息

Sacramento Zoo, 3930 West Land Park Drive, Sacramento, California 95822, USA.

出版信息

J Zoo Wildl Med. 2011 Dec;42(4):759-62. doi: 10.1638/2011-0033.1.

DOI:10.1638/2011-0033.1

PMID:22204079

Abstract

A 19-yr-old intact male Coquerel's sifaka (Propithecus coquereli) was evaluated for a crusting facial dermatopathy. Fungal culture and histopathology of skin biopsies were consistent with dermatophytosis caused by Trichophyton mentagrophytes, and treatment with the antifungal medication terbinafine was initiated. After 1 mo of treatment, all clinical signs had resolved and a fungal culture of the skin was negative. The sifaka was treated with terbinafine for a total of 81 days. Two additional fungal cultures were taken and found to be negative for the presence of dermatophytes, the last culture being taken 1 mo after discontinuation of terbinafine. To the authors' knowledge, this is the first reported case of dermatophytosis in a prosimian species and the first reported treatment of a prosimian with the antifungal drug terbinafine.

摘要

一只19岁的未阉割雄性科氏驯狐猴（Propithecus coquereli）因面部结痂性皮肤病接受评估。皮肤活检的真菌培养和组织病理学结果与须癣毛癣菌引起的皮肤癣菌病相符，遂开始使用抗真菌药物特比萘芬进行治疗。治疗1个月后，所有临床症状均已消退，皮肤真菌培养结果为阴性。这只驯狐猴总共接受了81天的特比萘芬治疗。又进行了两次真菌培养，结果显示未发现皮肤癣菌，最后一次培养是在停用特比萘芬1个月后进行的。据作者所知，这是灵长目原猴亚目物种中首例有报道的皮肤癣菌病病例，也是首例有报道的使用抗真菌药物特比萘芬治疗原猴亚目动物的病例。