Unité d'Epidémiologie des Maladies Emergentes, Institut Pasteur, Paris, France.
PLoS One. 2011;6(12):e28300. doi: 10.1371/journal.pone.0028300. Epub 2011 Dec 21.
Both pandemic and seasonal influenza are receiving more attention from mass media than ever before. Topics such as epidemic severity and vaccination are changing the way in which we perceive the utility of disease prevention. Voluntary influenza vaccination has been recently modeled using inductive reasoning games. It has thus been found that severe epidemics may occur because individuals do not vaccinate and, instead, attempt to benefit from the immunity of their peers. Such epidemics could be prevented by voluntary vaccination if incentives were offered. However, a key assumption has been that individuals make vaccination decisions based on whether there was an epidemic each influenza season; no other epidemiological information is available to them. In this work, we relax this assumption and investigate the consequences of making more informed vaccination decisions while no incentives are offered. We obtain three major results. First, individuals will not cooperate enough to constantly prevent influenza epidemics through voluntary vaccination no matter how much they learned about influenza epidemiology. Second, broadcasting epidemiological information richer than whether an epidemic occurred may stabilize the vaccination coverage and suppress severe influenza epidemics. Third, the stable vaccination coverage follows the trend of the perceived benefit of vaccination. However, increasing the amount of epidemiological information released to the public may either increase or decrease the perceived benefit of vaccination. We discuss three scenarios where individuals know, in addition to whether there was an epidemic, (i) the incidence, (ii) the vaccination coverage and (iii) both the incidence and the vaccination coverage, every influenza season. We show that broadcasting both the incidence and the vaccination coverage could yield either better or worse vaccination coverage than broadcasting each piece of information on its own.
大流行流感和季节性流感都比以往任何时候都受到大众媒体更多的关注。严重程度和疫苗接种等话题正在改变我们对疾病预防效用的看法。最近,利用归纳推理游戏对自愿流感疫苗接种进行了建模。结果发现,由于个体不接种疫苗,而是试图从同伴的免疫力中获益,可能会发生严重的疫情。如果提供激励措施,此类疫情是可以通过自愿接种疫苗来预防的。然而,一个关键的假设是,个体根据每个流感季节是否发生疫情来做出接种疫苗的决定;他们无法获得其他流行病学信息。在这项工作中,我们放宽了这一假设,并研究了在没有激励措施的情况下做出更明智的疫苗接种决策的后果。我们得到了三个主要结果。第一,无论个体对流感流行病学了解多少,他们都不会通过自愿接种疫苗来充分合作,以持续预防流感疫情。第二,传播比是否发生疫情更丰富的流行病学信息可以稳定疫苗接种率并抑制严重的流感疫情。第三,稳定的疫苗接种率遵循接种益处的趋势。然而,向公众发布更多的流行病学信息可能会增加或降低接种疫苗的感知益处。我们讨论了三种个体除了知道是否发生疫情之外,还知道(i)发病率,(ii)疫苗接种率以及(iii)每个流感季节的发病率和疫苗接种率的情况。我们表明,广播发病率和疫苗接种率可能会产生比单独广播每条信息更好或更差的疫苗接种率。