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种植牙手术的静脉镇静:咪达唑仑、布托啡诺和右美托咪定与咪达唑仑、布托啡诺和丙泊酚的比较。

Intravenous sedation for implant surgery: midazolam, butorphanol, and dexmedetomidine versus midazolam, butorphanol, and propofol.

作者信息

Kawaai Hiroyoshi, Tomita Shu, Nakaike Yoshihiro, Ganzberg Steven, Yamazaki Shinya

机构信息

1  Department of Dental Anesthesiology, Ohu University School of Dentistry, Fukushima, Japan.

出版信息

J Oral Implantol. 2014 Feb;40(1):94-102. doi: 10.1563/AAID-JOI-D-11-00200. Epub 2011 Dec 29.

Abstract

We compared the amnesic action, recovery process, and satisfaction of patients and surgeons after the use of 2 different sedation regimens for 40 patients undergoing scheduled implant surgery. Butorphanol, midazolam, dexmedetomidine (BMD) was administered to 20 patients who were maintained with continuous infusion of dexmedetomidine after the induction with butorphanol and midazolam, and butorphanol, midazolam, propofol (BMP) was administered to 20 patients who were maintained with continuous infusion of propofol after the induction with butorphanol and midazolam. To assess the amnesic action, the memory of local anesthesia, auditory memory, and visual memory were evaluated. The Trieger Dot Test (TDT) was applied during the recovery process. A questionnaire regarding the patient's feelings of the management of sedation was taken from each patient and was also filled out by the surgeon. The comparison between groups was analyzed by the Mann-Whitney U test. No significant differences in the amnesic action and the TDT were noted. Both methods also satisfied the patients and surgeons, as determined by the questionnaire results. In conclusion, both sedation regimens are appropriate for implant surgery.

摘要

我们比较了对40例计划接受种植手术的患者使用两种不同镇静方案后的遗忘作用、恢复过程以及患者和外科医生的满意度。对20例患者给予布托啡诺、咪达唑仑、右美托咪定(BMD),在布托啡诺和咪达唑仑诱导后持续输注右美托咪定维持;对另外20例患者给予布托啡诺、咪达唑仑、丙泊酚(BMP),在布托啡诺和咪达唑仑诱导后持续输注丙泊酚维持。为评估遗忘作用,对局部麻醉记忆、听觉记忆和视觉记忆进行了评估。在恢复过程中应用了特里格点试验(TDT)。从每位患者处获取了一份关于患者对镇静管理感受的问卷,外科医生也填写了该问卷。采用曼-惠特尼U检验分析组间差异。在遗忘作用和TDT方面未发现显著差异。根据问卷结果,两种方法均使患者和外科医生满意。总之,两种镇静方案均适用于种植手术。

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