Mamishi Setareh, Ahmadi Faezeh, Ahmadi Maedeh, Rezaei Nima
Tehran University of Medical Sciences Infectious Disease Research Center Tehran Iran.
Acta Microbiol Immunol Hung. 2011 Dec;58(4):297-301. doi: 10.1556/AMicr.58.2011.4.6.
Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disease, affecting phagocytic blood cells, which predispose patients to recurrent infectious complications. Herein, an 11-year-old girl is described who presented with liver abscess at the age of 9 years. Positive dihydrorhodamine (DHR) and nitrobluetetrazolium (NBT) tests confirmed the diagnosis of CGD for the patient. Anti-tuberculosis drugs and parenteral antibiotic therapy were started. Unusual visceral abscess and recurrent infections should be considered as an alarm for primary immunodeficiency diseases, while early diagnosis and appropriate treatment could prevent severe complications and even death in this group of patients.
