École de psychologie, Université Laval, 2325 rue des Bibliothèques, Quebec City, Quebec, Canada.
J Affect Disord. 2012 Mar;137(1-3):161-4. doi: 10.1016/j.jad.2011.12.001. Epub 2011 Dec 29.
Anxiety disorders are highly prevalent among patients with bipolar disorder and have a substantial impact on the course of illness and response to treatment. Despite the substantial impact that comorbid anxiety disorders have on the prognosis of individuals with bipolar disorder, many aspects of this comorbidity have received little attention from researchers. This study aims to document the current state of the literature on the comorbidity between anxiety and bipolar disorders by analyzing publication trends on the subject.
This study is a quantitative and qualitative review of articles on the comorbidity between anxiety disorders and bipolar disorder published between 1990 and 2010 in the ISI Web of Science, Medline and PsycINFO databases. The number of articles published each year on this comorbidity was calculated and compared to the literature published on bipolar disorder as a whole. Articles were classified into five categories and 13 subcategories to identify the main focuses of the literature and current gaps in the knowledge on the subject.
Interest in the comorbidity between anxiety disorders and bipolar disorder grew continually since 1990, but seems to have reached a plateau. The majority of articles addressing this comorbidity are descriptive in nature, with very few concrete studies examining the mechanisms and treatment approaches that might lead to positive advancements in the field.
Articles written in languages other than English or French were not reviewed.
It is time to step up research efforts to better understand and manage this under-studied combination of disorders.
焦虑障碍在双相情感障碍患者中非常普遍，对疾病过程和治疗反应有重大影响。尽管共病焦虑障碍对双相情感障碍个体的预后有很大影响，但研究人员对这种共病的许多方面关注甚少。本研究旨在通过分析该主题的出版物趋势，记录焦虑与双相情感障碍共病的文献现状。
这是一项对 1990 年至 2010 年间在 ISI Web of Science、Medline 和 PsycINFO 数据库中发表的关于焦虑障碍与双相情感障碍共病的文章进行的定量和定性回顾。计算了每年发表的关于这种共病的文章数量，并与作为一个整体发表的关于双相情感障碍的文献进行了比较。文章分为五类和十三个子类，以确定文献的主要焦点和当前该主题知识的空白。
自 1990 年以来，对焦虑障碍与双相情感障碍共病的兴趣持续增长，但似乎已经达到了一个平台期。大多数涉及这种共病的文章都是描述性的，很少有具体的研究探讨可能导致该领域取得积极进展的机制和治疗方法。
未审查用英语或法语以外的语言撰写的文章。
现在是加强研究努力的时候了，以更好地理解和管理这种研究不足的疾病组合。
