Nicolini U, Tannirandorn Y, Gonzalez P, Fisk N M, Beacham J, Letsky E A, Rodeck C H
Royal Postgraduate Medical School, Institute of Obstetrics and Gynecology, Queen Charlotte's and Chelsea Hospital, London, United Kingdom.
Am J Obstet Gynecol. 1990 Oct;163(4 Pt 1):1144-6. doi: 10.1016/0002-9378(90)90674-v.
Two patients with severe alloimmune thrombocytopenia were managed by weekly intrauterine platelet transfusions at 25 to 36 weeks. In one patient high-dose immunoglobulin was also administered weekly to the mother, and high maternal and fetal immunoglobulin levels were achieved. Fetal platelet counts were similar in both patients. The only variable that affected fetal platelet concentration was the posttransfusion platelet count from the previous transfusion.
两名患有严重同种免疫性血小板减少症的患者在孕25至36周时接受了每周一次的宫内血小板输注治疗。其中一名患者，还每周给母亲注射高剂量免疫球蛋白，使母体和胎儿的免疫球蛋白水平都达到了较高水平。两名患者的胎儿血小板计数相似。影响胎儿血小板浓度的唯一变量是前一次输血后的输血后血小板计数。
