Suppr超能文献

对芬兰东南部 221 例髋部骨折患者的长期随访:生存分析及既往或后继骨折。

A long-term follow-up of 221 hip fracture patients in southeastern Finland: analysis of survival and prior or subsequent fractures.

机构信息

Department of Orthopaedics and Traumatology, North-Kymi Hospital, FI-45750 Kuusankoski, Finland.

出版信息

Arch Gerontol Geriatr. 2012 May-Jun;54(3):e294-9. doi: 10.1016/j.archger.2011.12.002. Epub 2011 Dec 28.

Abstract

UNLABELLED

To analyze the type and effect of prior and subsequent fractures in a hip fracture cohort.

MATERIALS AND METHODS

Hip fracture patients (n=221) were followed for a mean of 8 years and all prior and subsequent fractures were studied. Incidence of the first fracture and subsequent fractures according to sex, age group, and time between the first and the index hip fracture were measured. The absolute fracture risk was measured in the study subjects and in the age groups <75 years and ≥75 years. Patients' survival was analyzed with the life-table method.

RESULTS

One third of the hip fracture patients had sustained previous fractures. In men, these were mostly ankle or hip fractures, and in women, wrist fractures. Of the subjects, 24% suffered a subsequent fracture, which in both sexes was usually a second hip fracture. At the end of the 8-year follow-up, 74% of the patients had died. The observed absolute fracture risk was 7% at one year and 24% at 5 years. In women, excess mortality was lowest during the first 4.8 years after the index hip fracture among patients with one fracture. However, it was highest among women with two fractures. In men, excess mortality was lowest among those with two fractures and highest among those with ≥3 fractures. There were no differences between the genders in sustaining subsequent fractures.

CONCLUSIONS

The fracture risk subsequent to hip fracture was similar in both genders. Patients with prior hip fractures had the worst survival rate.

摘要

目的

分析髋部骨折队列中既往和后继骨折的类型和影响。

材料和方法

对 221 例髋部骨折患者进行了平均 8 年的随访,并对所有既往和后继骨折进行了研究。测量了首次骨折和后继骨折的发生率,按性别、年龄组和首次与索引髋部骨折之间的时间进行分组。在研究对象和<75 岁和≥75 岁年龄组中测量绝对骨折风险。用寿命表法分析患者的生存情况。

结果

三分之一的髋部骨折患者既往有骨折。男性既往骨折多为踝关节或髋部骨折,女性多为腕部骨折。24%的患者发生了后继骨折,男女均为第二次髋部骨折。在 8 年的随访结束时,74%的患者已经死亡。观察到的 1 年绝对骨折风险为 7%,5 年时为 24%。在女性中,首次髋部骨折后 4.8 年内,有一次骨折的患者的超额死亡率最低。然而,有两次骨折的女性的超额死亡率最高。在男性中,有两次及以上骨折的患者的超额死亡率最低,有三次及以上骨折的患者的超额死亡率最高。在发生后继骨折方面,男女之间没有差异。

结论

髋部骨折后继发骨折的风险在两性中相似。有既往髋部骨折的患者生存率最差。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验