Department of Dermatology, National Defense Medical Center, Tri-Service General Hospital, Taipei, Taiwan.
Clin Exp Dermatol. 2012 Jul;37(5):501-4. doi: 10.1111/j.1365-2230.2011.04257.x. Epub 2011 Dec 23.
Botryomycosis is an uncommon chronic suppurative granulomatous bacterial infection that can affect the skin and viscera. Clinically, lesions typically consist of small tender nodules from which draining sinuses may develop to expel a purulent discharge. Histopathological features include characteristic aggregation of microorganisms (grain) within the inflammatory infiltrate. The commonest causative organisms are Staphylococcus aureus and Pseudomonas aeruginosa, of others. Botryomycosis resulting from Prevotella melaninogenica has not been reported previously. We report the case of a middle-aged patient with botryomycosis presenting as nasal cutaneous fistulas caused by P. melaninogenica, which was successfully treated with surgical intervention combined with systemic antibiotic treatment.
芽生菌病是一种罕见的慢性化脓性肉芽肿性细菌性感染,可影响皮肤和内脏。临床上,病变通常由小的触痛性结节组成,这些结节可能会发展出排脓的窦道。组织病理学特征包括在炎症浸润中特征性聚集的微生物(颗粒)。最常见的病原体是金黄色葡萄球菌和铜绿假单胞菌,其他还有一些。以前没有报道过由普雷沃氏菌引起的芽生菌病。我们报告了一例中年患者,患有芽生菌病,表现为普雷沃氏菌引起的鼻皮瘘管,经手术干预联合全身抗生素治疗后成功治愈。