Saadat P, Ram R, Sohrabian S, Vadmal M S
Department of Dermatology, University of Southern California-Keck School of Medicine, Los Angeles, CA, USA.
Clin Exp Dermatol. 2008 May;33(3):266-9. doi: 10.1111/j.1365-2230.2007.02612.x. Epub 2007 Dec 20.
Botryomycosis is an uncommon, chronic, granulomatous and/or suppurative, opportunistic infection affecting the skin and viscera, primarily caused by bacteria. The exact pathogenesis of this infection is not well understood. However, both the host's immune status and microbial infectivity have been implicated in the pathogenesis of this unusual clinical condition. To date, botryomycosis caused by a nonbacterial pathogen has not been reported in the literature. We report a case of cutaneous botryomycosis caused by combined Staphylococcus aureus and Pneumocystis carinii. Cutaneous P. carinii infection without pulmonary involvement is extremely rare.
葡萄状菌病是一种罕见的、慢性的、肉芽肿性和/或化脓性的机会性感染，主要影响皮肤和内脏，由细菌引起。这种感染的确切发病机制尚不清楚。然而，宿主的免疫状态和微生物感染性都与这种不寻常临床病症的发病机制有关。迄今为止，文献中尚未报道由非细菌性病原体引起的葡萄状菌病。我们报告一例由金黄色葡萄球菌和卡氏肺孢子虫合并感染引起的皮肤葡萄状菌病。无肺部受累的皮肤卡氏肺孢子虫感染极为罕见。
