Kipshidze N N, Chapidze G E, Bokhua M R, Marsagishvili L A, Dolidze N K, Eristavi D G
Research Institute of Experimental and Clinical Therapy, Tbilisi, U.S.S.R.
Angiology. 1990 Sep;41(9 Pt 2):801-8.
The efficacy of a new method of treatment, endovascular blood irradiation with He-Ne laser, developed by the authors, was studied in 295 patients with primary acute transmural myocardial infarction (MI). Twenty-four-hour Holter monitoring findings before and after laser irradiation suggested the possibility of preventing sudden death in the acute period of MI owing to the high anti-arrhythmic efficacy of the method with respect to high-grade ventricular arrhythmias. Precodial ECG mapping and serial determination of blood enzyme activities (CPK and MB-CPK) showed that irradiation performed within the first hours of MI development contributed to effective limitation of the infarction area and restricted the spread of the area of myocardial ischemic damage.
作者研发的一种新的治疗方法——氦氖激光血管内血液照射，在295例原发性急性透壁性心肌梗死（MI）患者中进行了疗效研究。激光照射前后的24小时动态心电图监测结果表明，由于该方法对高度室性心律失常具有较高的抗心律失常疗效，因此有可能预防MI急性期的猝死。胸前心电图标测和血液酶活性（CPK和MB-CPK）的系列测定表明，在MI发生后的最初几小时内进行照射有助于有效限制梗死面积，并限制心肌缺血损伤区域的扩散。
