[使用西沙必利治疗胃食管反流和消化性食管炎的结果]
[Results of the treatment of gastroesophageal reflux and peptic esophagitis using cisapride].
作者信息
Carrasco Gandía S, Lama Moré R, Prieto Bozano G, Polanco Allue I
机构信息
Unidad de Gastroenterología y Nutrición, Hospital Infantil de la Seguridad Social La Paz, Madrid.
出版信息
An Esp Pediatr. 1990 Jun;32(6):485-8.
PMID:2221622
Abstract
Cisapride is a new prokinetic agent that acts at gastric emptying, esophagic peristalsis and the pressure of the low esophagic sphincter. In the present study we grave Cisapride for 12 weeks to 34 patients with severe pathologic gastroesophageal reflux and/or peptic esophagitis. The results show an important improvement of the clinic, pH monitoring, endoscopic and histologic alterations.
摘要
西沙必利是一种新型促动力药，作用于胃排空、食管蠕动及食管下括约肌压力。在本研究中，我们对34例患有严重病理性胃食管反流和/或消化性食管炎的患者给予西沙必利治疗12周。结果显示临床症状、pH监测、内镜及组织学改变均有显著改善。
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