School of Population Health, University of Queensland, Brisbane, Australia.
Subst Use Misuse. 2012 Jan;47(1):78-85. doi: 10.3109/10826084.2011.629017.
Buprenorphine/naloxone has recently been introduced in Australia and is available for unsupervised dosing within Queensland. A retrospective observational study of data collected during 2000-2007 for clients obtaining injecting equipment from the Brisbane Harm Reduction Centre in Queensland is presented. The numbers of service occasions and needles and syringes were used as surrogate drug use measures. Buprenorphine and naloxone were misused at lower rates when compared with buprenorphine and methadone. Furthermore, the misuse of opioid replacement therapies represented less than 5% of all illicit opioid injections. Implications and study limitations are discussed.
丁丙诺啡/纳洛酮最近在澳大利亚推出，并可在昆士兰州进行无人监督的剂量给药。本研究呈现了 2000-2007 年期间昆士兰州布里斯班减少伤害中心为获取注射设备的客户所收集的数据的回顾性观察研究。服务次数、针和注射器的数量被用作替代药物使用的衡量标准。与丁丙诺啡和美沙酮相比，丁丙诺啡/纳洛酮的滥用率较低。此外，阿片类药物替代疗法的滥用不到所有非法阿片类药物注射的 5%。讨论了研究的意义和局限性。
