Cheah J S, Wang K W, Sum C F
Department of Medicine, National University Hospital, Singapore.
Ann Acad Med Singap. 1990 Jul;19(4):501-5.
The complex interaction between genetic and environmental factors in the causation of diabetes mellitus is well illustrated by the epidemiology of diabetes in the Asia-Pacific region. Among the Chinese, the prevalence of diabetes is uniformly higher among Chinese living outside China than in the Chinese in The People's Republic of China. Similarly among the Indians, the prevalence of diabetes is universally higher in those who have settled outside India than in Indians in India. In the Pacific populations, diabetes is much commoner among the Nauruans and Fiji Indians. Throughout the Asia-Pacific countries, economic progress and urbanisation have a uniformly deleterious effect on diabetes. A better understanding of the hereditary and environmental factors in the causation of diabetes is required to halt and reverse the rising prevalence of diabetes in the Asia-Pacific region.
亚太地区糖尿病的流行病学很好地说明了遗传因素与环境因素在糖尿病病因中的复杂相互作用。在中国人群中，生活在中国境外的华人糖尿病患病率普遍高于中华人民共和国境内的华人。同样，在印度人群中，定居在印度境外的人糖尿病患病率普遍高于印度境内的印度人。在太平洋地区的人群中，瑙鲁人和斐济印度人患糖尿病的情况更为普遍。在整个亚太国家，经济发展和城市化对糖尿病均产生有害影响。为了阻止并扭转亚太地区糖尿病患病率不断上升的趋势，需要更好地了解糖尿病病因中的遗传和环境因素。
