Quintens H, Chevallier D, Michels J F, Padovani B, Villers A, Amiel J, Toubol J
Service d'Urologie, CHU de Nice, Hôpital Pasteur.
Ann Urol (Paris). 1990;24(4):335-9.
Spread beyond the capsule is a poor prognosis factor in clinically localized carcinomas of the prostate; preoperative diagnosis is difficult and clinical evaluation usually underestimates tumor spread. This prospective study was undertaken to confront results of the conventional workup (rectal examination, transrectal ultrasonography and PSA) and of CT scan and MRI findings with findings upon the pathologic study of operative specimens following radical prostatectomy. Results show that the conventional workup remains the diagnostic gold standard and that CT scan yields no additional information. Technically faultless MRI with sections in the three planes is a good means for analyzing the capsule of the prostate.
在临床局限性前列腺癌中,肿瘤突破包膜是预后不良的因素;术前诊断困难,临床评估通常会低估肿瘤的扩散情况。本前瞻性研究旨在对比传统检查(直肠指检、经直肠超声检查和前列腺特异性抗原)以及CT扫描和MRI检查结果与根治性前列腺切除术后手术标本病理研究结果。结果显示,传统检查仍是诊断的金标准,CT扫描未提供额外信息。技术上完美的三平面MRI切片是分析前列腺包膜的良好手段。