Department of Family Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.
J Am Board Fam Med. 2012 Jan-Feb;25(1):9-15. doi: 10.3122/jabfm.2012.01.110164.
Though the benefits of healthy lifestyle choices are well-established among the general population, less is known about how developing and adhering to healthy lifestyle habits benefits obese versus normal weight or overweight individuals. The purpose of this study was to determine the association between healthy lifestyle habits (eating 5 or more fruits and vegetables daily, exercising regularly, consuming alcohol in moderation, and not smoking) and mortality in a large, population-based sample stratified by body mass index (BMI).
We examined the association between healthy lifestyle habits and mortality in a sample of 11,761 men and women from the National Health and Nutrition Examination Survey III; subjects were ages 21 and older and fell at various points along the BMI scale, from normal weight to obese. Subjects were enrolled between October 1988 and October 1994 and were followed for an average of 170 months.
After multivariable adjustment for age, sex, race, education, and marital status, the hazard ratios (95% CIs) for all-cause mortality for individuals who adhered to 0, 1, 2, or 3 healthy habits were 3.27 (2.36-4.54), 2.59 (2.06-3.25), 1.74 (1.51-2.02), and 1.29 (1.09-1.53), respectively, relative to individuals who adhered to all 4 healthy habits. When stratified into normal weight, overweight, and obese groups, all groups benefited from the adoption of healthy habits, with the greatest benefit seen within the obese group.
Healthy lifestyle habits are associated with a significant decrease in mortality regardless of baseline body mass index.
尽管健康生活方式选择的益处已在普通人群中得到充分证实,但对于养成和坚持健康生活习惯如何使肥胖者受益,相对于体重正常或超重者而言,了解甚少。本研究旨在确定健康生活习惯(每天食用 5 份或更多份水果和蔬菜、经常锻炼、适量饮酒和不吸烟)与基于体重指数(BMI)分层的大型人群样本中死亡率之间的关系。
我们检查了 11761 名来自国家健康与营养调查 III 研究的男性和女性样本中健康生活习惯与死亡率之间的关联;受试者年龄在 21 岁及以上,处于 BMI 从正常体重到肥胖的各个阶段。参与者于 1988 年 10 月至 1994 年 10 月间登记,并平均随访 170 个月。
经过多变量调整年龄、性别、种族、教育程度和婚姻状况后,坚持 0、1、2 或 3 种健康习惯的个体全因死亡率的风险比(95%CI)分别为 3.27(2.36-4.54)、2.59(2.06-3.25)、1.74(1.51-2.02)和 1.29(1.09-1.53),相对于坚持所有 4 种健康习惯的个体。当按体重正常、超重和肥胖组分层时,所有组都从养成健康习惯中受益,肥胖组受益最大。
无论基线 BMI 如何,健康的生活习惯都与死亡率显著降低相关。