Kang Xiao-Jun, Sui Xiao-Dong
Xiamen Children's Hospital/Children's Hospital of Fudan University at Xiamen, Xiamen, Fujian, 361006, China.
Xingbin Street Community Health Service Center in Jimei District, Xiamen City, Xiamen, Fujian, 361021, China.
BMC Pediatr. 2024 Jul 31;24(1):489. doi: 10.1186/s12887-024-04967-w.
With the increasing prevalence of overweight and obesity in children and adolescents, to actively prevent the occurrence of asthma in this population is important for reducing the burden of the disease. Lifestyle factors, including diet and exercise, are importance for overweight and obese adolescents, as well as an important modifiable factor affecting airway inflammation and asthma, whether healthy lifestyle was correlated with the risk of asthma in adolescents ≥ 12 years has not been reported. We suspected that there might be correlation between healthy lifestyle behaviors and the risk of asthma in overweight and obese adolescents. This cross-sectional study aimed to explore the association between the adherence to a healthy lifestyle behaviors and the risk of asthma in overweight and obese adolescents based on the data of 945 participants aged between 12-18 years from the National Health and Nutrition Examination Surveys (NHANES). Univariable and multivariable weighted Logistic regression models were applied to evaluate the association between healthy lifestyle behaviors with asthma risk in overweight and obese adolescents. Odds ratio (OR) and 95% confidence interval (CI) were applied as estimates. We found that the risk of asthma was reduced in overweight and obese adolescents with intermediate (OR = 0.40, 95%CI: 0.17-0.94) or good lifestyle behaviors (OR = 0.33, 95%CI: 0.13-0.86) in comparison to those with poor lifestyle behaviors. In summary, intermediate or good lifestyle behaviors was correlated with decreased risk of asthma in overweight and obese adolescents, which might provide a reference for making further prevention strategies for asthma in adolescents.
随着儿童和青少年超重及肥胖患病率的不断上升,积极预防该人群哮喘的发生对于减轻疾病负担至关重要。生活方式因素,包括饮食和运动,对超重和肥胖青少年很重要,也是影响气道炎症和哮喘的一个重要可改变因素,然而,健康的生活方式与12岁及以上青少年哮喘风险之间是否存在关联尚未见报道。我们怀疑健康的生活方式行为与超重和肥胖青少年的哮喘风险之间可能存在关联。这项横断面研究旨在基于美国国家健康与营养检查调查(NHANES)中945名年龄在12至18岁之间参与者的数据,探讨超重和肥胖青少年坚持健康生活方式行为与哮喘风险之间的关联。采用单变量和多变量加权Logistic回归模型来评估超重和肥胖青少年健康生活方式行为与哮喘风险之间的关联。比值比(OR)和95%置信区间(CI)用作估计值。我们发现,与生活方式行为较差的超重和肥胖青少年相比,生活方式行为中等(OR = 0.40,95%CI:0.17 - 0.94)或良好(OR = 0.33,95%CI:0.13 - 0.86)的超重和肥胖青少年哮喘风险降低。总之,中等或良好的生活方式行为与超重和肥胖青少年哮喘风险降低相关,这可能为制定青少年哮喘进一步预防策略提供参考。