Department of General Surgery, State University of Maringá (UEM), University Hospital, Av. Mandacarú, 1590, Maringá, PR 87083-240, Brazil.
Surg Endosc. 2012 Jun;26(6):1724-9. doi: 10.1007/s00464-011-2099-x. Epub 2012 Jan 5.
In prolonged laparoscopic procedures, hypothermia is frequently observed. The possible influence of the vasodilating action of CO(2), due to its increased levels in the blood during the laparoscopic procedures, has yet to be studied. The objective of this study was, therefore, to evaluate body temperature patterns in pigs subjected to pneumoperitoneum with CO(2).
Thirty male pigs were allocated into three groups of ten animals each: group I, anesthetic procedure and abdominal puncture only; group II, the same as for group I and insufflation with CO(2); and group III, the same as for group I and insufflation with medical grade compressed air. After anesthetic induction and surgical preparation, rectal and esophageal temperatures were measured every 10 min. Blood was collected during the experiment for the gasometric measurement of pCO(2). Animals were insufflated with no gas loss and were kept anesthetized for 180 min. For statistical analysis, Friedman and Kruskal-Wallis tests were used at a level of significance of 95% (P < 0.05).
Animals in groups I and II (P = 0.000) had a statistically significant drop in both esophageal and rectal temperatures during the experiment, but not animals in group III. However, when the groups were compared among themselves, no statistically significant differences were found at any of the times measured. A statistically significant drop in pCO(2) levels was observed for groups I and III, but not for animals in groups II.
The use of CO(2) did not significantly affect body temperature variation in pigs subjected to pneumoperitoneum. However, CO(2) produced a temperature drop pattern different than that of compressed air, indicating that CO(2) may lead to thermoregulatory changes and influence the peripheral temperature drop.
在长时间的腹腔镜手术中，经常会出现低体温。由于腹腔镜手术过程中血液中 CO₂水平升高，CO₂的血管扩张作用可能会产生影响，但尚未对此进行研究。因此，本研究旨在评估 CO₂气腹对猪体温模式的影响。
将 30 只雄性猪随机分为三组，每组 10 只：I 组，仅进行麻醉和腹部穿刺；II 组，与 I 组相同，并用 CO₂充气；III 组，与 I 组相同，用医用压缩空气充气。麻醉诱导和手术准备后，每 10 分钟测量直肠和食管温度。实验过程中采集血液进行血气测量 pCO₂。动物在无气体损失的情况下充气，并保持麻醉 180 分钟。统计分析采用 Friedman 和 Kruskal-Wallis 检验，显著性水平为 95%（P < 0.05）。
I 组和 II 组（P = 0.000）的动物在实验过程中食管和直肠温度均明显下降，但 III 组动物没有。然而，当组间比较时，在测量的任何时间点均未发现统计学差异。I 组和 III 组的 pCO₂水平明显下降，但 II 组动物没有。
在接受气腹的猪中，使用 CO₂不会显著影响体温变化。然而，CO₂产生的体温下降模式与压缩空气不同，表明 CO₂可能导致体温调节变化并影响外周体温下降。
