Huaman J A, Castillo M C
Hospital Generale Base Cayetano Heredia, Lima, Pérou.
Arch Anat Cytol Pathol. 1990;38(4):135-42.
Two hundred and three skin and mucosal biopsies performed in 162 patients suffering from leishmaniasis, were studied retrospectively. They were classified according to Ridley into 5 histological groups of increasing severity. In cutaneous leishmaniasis, a high proportion of the biopsies belonged to groups III and IV. In mucocutaneous leishmaniasis, the percentage of groups III and VI was lower and group V was present in 20% of cases. In 16 patients, followed by repeated biopsies, we detected some variations of the histological group during the course of the disease. However, there were no positive correlations between clinicopathological features and prognosis.
对162例利什曼病患者进行的203份皮肤和黏膜活检标本进行了回顾性研究。根据里德利分类法,将其分为5个严重程度递增的组织学组。在皮肤利什曼病中,大部分活检标本属于III组和IV组。在黏膜皮肤利什曼病中,III组和VI组的百分比更低,V组出现在20%的病例中。在16例患者中,通过重复活检发现,在疾病过程中组织学组有一些变化。然而,临床病理特征与预后之间没有正相关。