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棘阿米巴角膜炎继发的晶状体上皮细胞死亡:白内障手术后六年囊袋未出现混浊

Lens epithelial cell death secondary to acanthamoeba keratitis: absence of capsular bag opacification six years after cataract surgery.

作者信息

Moreno-Montañés Javier, Barrio-Barrio Jesús, De-Nova Elisa, Werner Liliana

机构信息

Department of Ophthalmology, Clínica Universidad de Navarra, Facultad de Medicina, Universidad de Navarra, Pamplona, Spain.

出版信息

Case Rep Ophthalmol. 2011 Sep;2(3):354-9. doi: 10.1159/000334785. Epub 2011 Dec 2.

Abstract

PURPOSE

To show the evolution of anterior chamber structures 6 years after cataract surgery in a case with Acanthamoeba keratitis (AK).

METHODS

A 37-year-old woman with AK receiving long-term treatment with chlorhexidine, propamidine isethionate and steroids developed a white cataract and iris atrophy. Penetrating keratoplasty and cataract surgery were performed with subsequent intraocular pressure elevation requiring Molteno shunt implantation. Two years after the last surgery, endothelial decompensation developed and another penetrating keratoplasty was performed. Intraoperatively, the anterior and posterior capsules were completely transparent.

RESULTS

Six years after cataract surgery, the intraocular lens was centered with clear anterior and posterior capsules without lens epithelial cells proliferation. No Soemmering's ring formation or posterior capsule opacification was found. Also, no zonular damage or pseudophacodonesis was observed.

CONCLUSIONS

This case suggests that AK infection and AK treatment not only cause white progressive cataract but also lens epithelial cell death. The capsules may be completely clear 6 years after cataract surgery, with a good quality of vision regardless of intraocular lens material or design.

摘要

目的

展示棘阿米巴角膜炎(AK)患者白内障手术后6年前房结构的演变。

方法

一名37岁患有AK的女性长期接受氯己定、依西双胍和类固醇治疗,出现了白色白内障和虹膜萎缩。进行了穿透性角膜移植术和白内障手术,随后眼压升高,需要植入莫氏分流管。最后一次手术后两年,发生了内皮失代偿,又进行了一次穿透性角膜移植术。术中,前后囊膜完全透明。

结果

白内障手术后6年,人工晶状体居中,前后囊膜清晰,无晶状体上皮细胞增殖。未发现Soemmering环形成或后囊膜混浊。此外,未观察到悬韧带损伤或人工晶状体震颤。

结论

该病例表明,AK感染和AK治疗不仅会导致白色进行性白内障,还会导致晶状体上皮细胞死亡。白内障手术后6年,囊膜可能完全清晰,无论人工晶状体的材料或设计如何,视力质量都良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5265/3250659/a77f7eb18ad5/cop0002-0354-f01.jpg

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