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人类记忆的神经生物学

The neurobiology of the human memory.

作者信息

Fietta Pierluigi, Fietta Pieranna

机构信息

Dipartimento di Psichiatria, A,ienda Ospedaliera di Lodi, Via Fleming 1, 26841 Casalpusterlengo, Lodi.

出版信息

Theor Biol Forum. 2011;104(1):69-87.

Abstract

Memory can be defined as the ability to acquire, process, store, and retrieve information. Memory is indispensable for learning, adaptation, and survival of every living organism. In humans, the remembering process has acquired great flexibility and complexity, reaching close links with other mental functions, such as thinking and emotions. Changes in synaptic connectivity and interactions among multiple neural networks provide the neurobiological substrates for memory encoding, retention, and consolidation. Memory may be categorized as short-term and long-term memory (according to the storage temporal duration), as implicit and explicit memory (with respect to the consciousness of remembering), as declarative (knowing that [fact]) and procedural (knowing how [skill]) memory, or as sensory (echoic, iconic and haptil), semantic, and episodic memory (according to the various remembering domains). Significant advances have been obtained in understanding memory neurobiology, but much remains to be learned in its cognitive, psychological, and phenomenological aspects.

摘要

记忆可被定义为获取、处理、存储和检索信息的能力。记忆对于每个生物体的学习、适应和生存而言不可或缺。在人类中,记忆过程具有极大的灵活性和复杂性,与思维和情感等其他心理功能建立了紧密联系。多个神经网络之间突触连接性和相互作用的变化为记忆编码、保留和巩固提供了神经生物学基础。记忆可根据存储的时间长短分为短期记忆和长期记忆,根据记忆的意识程度分为内隐记忆和外显记忆,根据记忆内容分为陈述性(知道[事实])和程序性(知道如何[技能])记忆,或者根据不同的记忆领域分为感觉(回声、图像和触觉)、语义和情景记忆。在理解记忆神经生物学方面已经取得了重大进展,但在其认知、心理和现象学方面仍有许多有待了解之处。

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