Hubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Huazhong Normal University, Wuhan 430079, China.
J Fish Biol. 2012 Jan;80(1):100-9. doi: 10.1111/j.1095-8649.2011.03153.x. Epub 2011 Nov 30.
Two pumilios, pum1 and pum2, were identified in medaka Oryzias latipes. Oryzias latipes pum1 and pum2 are ubiquitous in the adult tissues but with specific expression in the germ cells of gonads, ovary and testis. Pum1 is expressed in the spermatogonia to spermatocytes whilst pum2 presents in spermatocytes of testis only. Oryzias latipes pum1 and pum2 are maternally supplied RNA with ubiquitous expression in the early stages, and embryonic expression of pum1 and pum2 may begin from early gastrula. Both pum1 and pum2 are expressed in the tissues including brain, eye and trunk, and both are expressed in the gonads after hatching. Taken together, Pum1 and Pum2 may play important roles in embryonic and germ cell development of O. latipes.
两种 pumilio 基因， pum1 和 pum2，在鱼类斑马鱼中被鉴定出来。斑马鱼 pum1 和 pum2 在成年组织中普遍存在，但在性腺、卵巢和睾丸的生殖细胞中具有特异性表达。Pum1 在精原细胞到精母细胞中表达，而 pum2 仅在睾丸的精母细胞中存在。斑马鱼 pum1 和 pum2 是母体提供的 RNA，在早期具有普遍表达，并且 pum1 和 pum2 的胚胎表达可能从早期原肠胚开始。Pum1 和 Pum2 都在包括大脑、眼睛和躯干在内的组织中表达，并且在孵化后都在性腺中表达。综上所述，Pum1 和 Pum2 可能在 O. latipes 的胚胎和生殖细胞发育中发挥重要作用。
