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[一名类风湿关节炎患者合并脊髓空洞症和延髓空洞症的血管母细胞瘤]

[Hemangioblastoma associated with syringomyelia and syringobulbia in a patient with rheumatoid arthritis].

作者信息

Bonet M, Arnau D, Roquer J, Matias-Guiu X, Oliver B

机构信息

Hospital de l'Esperança, Servicios de Reumatología y Neurología.

出版信息

Arch Neurobiol (Madr). 1990 Mar-Apr;53(2):89-91.

PMID:2222128
Abstract

A 80-year-old woman with a 25-year history of seropositive, erosive rheumatoid arthritis (RA) presented with a neurological clinical picture consistent with cervical cord compression, secondary to a hemangioblastoma with medulla, cerebellum and spinal cord involvement, with associated syringomyelia and syringobulbia. We present a review of the literature remarking the low frequency of this tumor (1%-2% of all intracranial tumors) and its exceptional presentation over the age of 70. We have not been able to find no cases of hemangioblastoma associated with rheumatoid arthritis, thus, we think, this association may be casual. Nevertheless, it emphasizes the need for careful evaluation of patients with rheumatoid arthritis and neurological symptoms before ascribing them to complications due to the rheumatoid disease itself.

摘要

一名80岁女性,有25年血清阳性、侵蚀性类风湿关节炎(RA)病史,出现与颈髓受压相符的神经学临床表现,继发于累及延髓、小脑和脊髓的血管母细胞瘤,并伴有脊髓空洞症和延髓空洞症。我们对文献进行了综述,指出该肿瘤发生率较低(占所有颅内肿瘤的1%-2%),且在70岁以上患者中表现罕见。我们未发现血管母细胞瘤与类风湿关节炎相关的病例,因此,我们认为这种关联可能是偶然的。尽管如此,这强调了在将类风湿关节炎患者出现的神经症状归因于类风湿疾病本身的并发症之前,需要对其进行仔细评估。

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