Adachi Y, Mori M, Sugimachi K
Second Department of Surgery, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Arch Pathol Lab Med. 1990 Oct;114(10):1046-8.
A small gastric carcinoma was detected in a man, but he refused surgery. Eight years later, he was readmitted for a check-up, and a partial gastrectomy was performed. Pathologic examination revealed a well-differentiated adenocarcinoma restricted within the mucosa. In another man, an irregularly shaped, grossly depressed lesion indicating a malignancy was present at the gastric angle, and 6 years later he agreed to a partial gastrectomy. The lesion proved to be a well-differentiated adenocarcinoma confined to the mucosa. Retrospective examination of the original biopsy specimen revealed a small area of adenocarcinoma, presumably overlooked at the initial examination. Thus, some gastric carcinomas of the well-differentiated type can grow at an extremely slow rate, without extensive spread or invasion. Findings in these cases contribute to knowledge of the biological behavior of gastric carcinomas.
一名男性被检测出患有小胃癌，但他拒绝手术。八年后，他再次入院检查，并接受了胃部分切除术。病理检查显示为高分化腺癌，局限于黏膜内。另一名男性在胃角处有一个形状不规则、肉眼可见凹陷的病变，提示为恶性肿瘤，6年后他同意接受胃部分切除术。病变证实为局限于黏膜的高分化腺癌。对原活检标本进行回顾性检查发现有一小片腺癌区域，可能在初次检查时被忽视了。因此，一些高分化型胃癌生长极其缓慢，无广泛扩散或浸润。这些病例的发现有助于了解胃癌的生物学行为。
