University of Florida College of Medicine, Gainesville, FL 32610-0278, USA.
Semin Hematol. 2012 Jan;49(1):104-9. doi: 10.1053/j.seminhematol.2011.10.004.
Over the last two decades quality of life (QoL) and the social challenges of allogeneic hematopoietic stem cell transplant (allo-HSCT) survivors have been emerging as subjects of extensive research and are now considered as very important aspects in the pretransplant evaluation and management of allo-HSCT recipients. Recognition of QoL challenges in allo-HSCT survivors allows timely interventions leading to improvement of post-transplant outcomes. It needs to be recognized that long-lasting life changes associated with survivorship after allo-HSCT also significantly affect QoL of partners of allo-HSCT survivors. Currently, resources should be focused on how research findings can be used by patients, their partners, and physicians to optimize QoL and psychosocial adjustment.
在过去的二十年中,生活质量(QoL)和异基因造血干细胞移植(allo-HSCT)幸存者的社会挑战已经成为广泛研究的主题,现在被认为是 allo-HSCT 受者移植前评估和管理中非常重要的方面。认识到 allo-HSCT 幸存者的 QoL 挑战可以及时进行干预,从而改善移植后的结果。需要认识到,与 allo-HSCT 后生存相关的持久生活变化也会显著影响 allo-HSCT 幸存者伴侣的 QoL。目前,资源应集中于如何利用研究结果使患者、其伴侣和医生能够优化 QoL 和心理社会调整。