Ivanovskaia T E
Arkh Patol. 1990;52(6):29-33.
The definition of the congenital immunodeficiency syndrome (CIDS) is given. Structural alterations of the thymus in combination with zonal disturbances and cell composition of the peripheral lymph organs are main morphological manifestations of CIDS. The most reasonable classification of CIDS is that based on etiology and thus making necessary to reconsider the existing terminology with an exclusion of such terms as "primary" and "secondary" immunodeficiency. The crucial point in the CIDS pathogenesis is a time of structural disturbances resulting from the action of an altering factor on the immune system in ontogenesis. A list of diseases of the histiomonocytic system is given which can be used as a basis for developing the classification of CIDS of the above system as the most ancient element in the immune response in the phylo- and ontogenesis.
给出了先天性免疫缺陷综合征（CIDS）的定义。胸腺的结构改变与外周淋巴器官的区域紊乱和细胞组成相结合是CIDS的主要形态学表现。CIDS最合理的分类是基于病因的分类，因此有必要重新考虑现有术语，排除“原发性”和“继发性”免疫缺陷等术语。CIDS发病机制的关键点是在个体发育过程中，改变因素作用于免疫系统导致结构紊乱的时期。给出了一组组织细胞单核细胞系统疾病清单，可作为将上述系统的CIDS分类作为系统发育和个体发育中免疫反应最古老元素的基础。
