Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong Special Administrative Region.
Vaccine. 2012 Feb 27;30(10):1895-900. doi: 10.1016/j.vaccine.2011.12.027. Epub 2012 Jan 2.
We described the monetary and non-monetary cost incurred by children hospitalized for virologically confirmed influenza virus infection in a population-based prospective 3-year study. The mean direct and indirect cost of each child hospitalized was $1217.82 (95% CI, 1111.54-1324.23) and $1328.33 (95% CI, $1136.79-1520.00) for influenza A and B, respectively. School age patients took a mean (SD) of 4.70 (3.05) days and 5.31 (3.62) days of sick leave for influenza A and B infection, respectively. Pediatric influenza A and B hospitalization was associated with 662-1046 days of school absenteeism and 214-336 days of parental work loss per 10,000 population <18 years of age per year. We showed that the cost incurred by hospitalization alone, was comparable to the cost of annual universal pediatric influenza vaccination especially in children 6 months to under 6 years of age and vaccination would result in much larger cost-savings when non-monetary costs are included.
我们在一项基于人群的前瞻性 3 年研究中描述了因病毒学确诊的流感病毒感染而住院的儿童所产生的货币和非货币成本。每例因流感 A 和 B 住院的儿童的平均直接和间接成本分别为 1217.82 美元（95%CI，1111.54-1324.23）和 1328.33 美元（95%CI，$1136.79-1520.00）。学龄患者因流感 A 和 B 感染分别平均请病假 4.70 天（3.05）和 5.31 天（3.62）。每 10000 名<18 岁人群中，儿科流感 A 和 B 住院与每年缺勤 662-1046 天和父母每年损失 214-336 天的工作时间有关。我们表明，仅住院费用就与每年普遍进行儿童流感疫苗接种的费用相当，尤其是在 6 个月至 6 岁以下儿童中，而当包括非货币成本时，疫苗接种将带来更大的成本节约。
