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化学交联的 MRI 纳米探针的自体荧光，实现治疗细胞的多模式成像。

Self-fluorescence of chemically crosslinked MRI nanoprobes to enable multimodal imaging of therapeutic cells.

机构信息

Graduate School and Department of Analytical Science and Technology, Chungnam National University, Daejeon 305-764, Republic of Korea.

出版信息

Small. 2012 Mar 12;8(5):666-70. doi: 10.1002/smll.201102361. Epub 2012 Jan 5.

DOI:10.1002/smll.201102361
PMID:22223602
Abstract

Old chemistry for novel materials: Self-fluorescent high-relaxivity T(2)-weighted magnetic resonance imaging (MRI) contrast agents are produced. They are a novel type of MR/optical dual-modality in vivo imaging nanoprobe using glutaraldehyde crosslinking chemistry, and they are used to label and monitor therapeutic cells both in vitro and in vivo.

摘要

旧化学新用途

制备具有自主荧光的高弛豫率 T2 加权磁共振成像（MRI）造影剂。这些造影剂是一种新型的基于磁共振/光学双模态的活体成像纳米探针，采用戊二醛交联化学方法制备，用于体外和体内标记和监测治疗细胞。

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