美国 HIV 阳性队列中的淋病或衣原体。
Gonorrhoea or chlamydia in a U.S. military HIV-positive cohort.
机构信息
University of Minnesota School of Public Health, 1300 S. Second Street, Suite 300, Minneapolis, MN 55454-1015, USA.
出版信息
Sex Transm Infect. 2012 Jun;88(4):266-71. doi: 10.1136/sextrans-2011-050173. Epub 2012 Jan 4.
OBJECTIVES
To investigate the epidemiology and risk factors of gonorrhoea (GC) or chlamydia (CT) coinfection in an HIV-positive US military cohort, focusing on the time after participants' knowledge of HIV diagnosis.
METHODS
The authors analysed data from 4461 participants enrolled in the U.S. Military Natural History Study cohort for GC or CT infection ≥6 months after their HIV-positive test.
RESULTS
During a mean follow-up of 7.08 years, 482 (11%) participants acquired a GC or CT infection. Of these, 283 (6%) acquired a GC infection, 278 (6%) acquired a CT infection and 123 (3%) had multiple GC or CT infections during follow-up. Risk of GC or CT infection was significantly greater in those younger, male, African-American and with a history of GC or CT infection.
CONCLUSIONS
Frequent GC and CT diagnoses observed among members of this HIV-positive cohort indicate substantial ongoing risk behaviours that raise concerns for HIV transmission and underscore the need for continued screening to help identify and treat these sexually transmitted infections in this population.
目的
调查 HIV 阳性美国军人队列中淋病（GC）或衣原体（CT）合并感染的流行病学和危险因素，重点关注参与者了解 HIV 诊断后的时间。
方法
作者分析了美国军事自然史研究队列中 4461 名参与者的数据，这些参与者在 HIV 阳性检测后至少 6 个月感染了 GC 或 CT。
结果
在平均 7.08 年的随访中，482 名（11%）参与者发生了 GC 或 CT 感染。其中，283 名（6%）发生了 GC 感染，278 名（6%）发生了 CT 感染，123 名（3%）在随访期间发生了多次 GC 或 CT 感染。在年龄较小、男性、非裔美国人以及有 GC 或 CT 感染史的参与者中，GC 或 CT 感染的风险显著增加。
结论
在 HIV 阳性队列的成员中频繁诊断出 GC 和 CT，表明存在大量持续的风险行为，这令人担忧 HIV 的传播，并强调需要继续进行筛查，以帮助识别和治疗该人群中的这些性传播感染。
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