Takehara M, Kuida K, Mori K
Arch Virol. 1979;59(3):269-74. doi: 10.1007/BF01317423.
Interferon (IF) induction and antiviral activity by purified spherical (S) or filamentous (F) virus-like particles and S-derived RNA was studied. A single administration of S particles prior to virus challenge reduced significantly the mortality of mice infected with western equine encephalitis (WEE) virus.
研究了纯化的球形(S)或丝状(F)病毒样颗粒以及源自S的RNA的干扰素(IF)诱导和抗病毒活性。在病毒攻击前单次给予S颗粒可显著降低感染西部马脑炎(WEE)病毒的小鼠死亡率。