Maksimova M Iu, Sharov M N, Sineva N A, Vodop'ianov N P
Zh Nevrol Psikhiatr Im S S Korsakova. 2011;111(8 Pt 2):35-40.
Efficacy of neuromidin was studied in 62 patients with a small ischemic stroke and cognitive disorders. Patients of the main group received neuromidin as an add-on to basic treatment and patients of the comparison group received only basic treatment (antiaggregant, antihypertensive, cardiac and antidiabetic drugs with the exclusion of nootropic and psychotropic medications). The decrease of subjective complaints, improvement of memory, attention, abstract and practical reasoning assessed by neuropsychological tests were seen in 32 patients of the main group after the end of treatment course. Neuromidin did not cause side-effects and was well tolerated. The long use of this led to the reduction of cognitive impairment, a predictor of vascular dementia.
对62例患有轻度缺血性中风和认知障碍的患者进行了神经调节素的疗效研究。主要组患者在基础治疗的基础上加用神经调节素,对照组患者仅接受基础治疗(抗血小板药物、抗高血压药物、心脏药物和抗糖尿病药物,但不包括促智药和精神药物)。治疗疗程结束后,主要组的32例患者主观症状减轻,神经心理测试评估的记忆力、注意力、抽象和实际推理能力得到改善。神经调节素未引起副作用,耐受性良好。长期使用该药物可减少认知障碍,而认知障碍是血管性痴呆的一个预测指标。