Department of Radiology, Maidstone Hospital, Maidstone, Kent, UK.
Clin Radiol. 2012 Jul;67(7):687-94. doi: 10.1016/j.crad.2011.11.009. Epub 2012 Jan 9.
Sentinel lymph node (SLN) biopsy has become the recommended method for surgical staging of the axilla in patients with breast cancer. Grey-scale axillary ultrasonography (US) combined with US-guided biopsy is a widely used preoperative staging procedure but has limited sensitivity. US contrast agent "microbubbles", when injected intradermally, have been shown to have the potential to enter the breast lymphatics, travel rapidly to the axilla, and visualize the putative SLNs. This review illustrates the SLN identification technique using intradermal injection of microbubbles and contrast-enhanced US. The injection method, lymphatic visualization techniques, grey-scale and contrast-enhanced US images of the putative SLNs are reviewed and exemplified.
前哨淋巴结（SLN）活检已成为乳腺癌患者腋窝手术分期的推荐方法。灰阶腋窝超声（US）联合 US 引导下活检是一种广泛应用的术前分期程序，但敏感性有限。经皮注射超声造影剂“微泡”已显示出有潜力进入乳腺淋巴管，快速到达腋窝，并可视化假定的 SLN。本综述说明了使用皮内注射微泡和对比增强超声进行 SLN 识别的技术。综述并举例说明了注射方法、淋巴管可视化技术、假定的 SLN 的灰阶和对比增强 US 图像。
