Rudat V, Brune-Erbe I, Noureldin A, Bushnag Z, Almuraikhi N, Altuwaijri S
Department of Radiation Oncology, Saad Specialist Hospital, Al Khobar, Saudi Arabia.
Gulf J Oncolog. 2012 Jan(11):45-9.
Breast cancer is the most common cancer in Saudi Arabia. However, detailed published epidemiologic data are scarce. In this study, breast cancer patients at a tertiary care hospital were characterized and compared with data from the United States.
Medical records were retrospectively reviewed of female patients with confirmed diagnosis of invasive breast cancer who consulted with Saad Specialist Hospital between 2004 and 2011. Descriptive statistics were calculated and compared with published data.
Two-hundred and sixty-two female patients with cytologically or histologically confirmed diagnosis of invasive breast cancer were identified and analyzed. Compared to published American data derived from the SEER database, patients were diagnosed at a markedly younger age (<50 years: 57.5% versus 12.5%) and more advanced disease (localized disease: 28.6% versus 61.2%). The difference of the age at diagnosis could not be fully explained by the different age structures of the Saudi Arabian and American population in our analysis. Although the overall mastectomy rate was higher (58.2% versus 38.5%), no relevant difference in the mastectomy rates was found if analyzed by stage.
Our data suggest that breast cancer in this part of Saudi Arabia is diagnosed at a much higher stage compared to the United States. More effort in awareness campaigns, easier access to screening and treatment are needed to improve the prognosis and to reduce the currently relatively high mastectomy rate.
乳腺癌是沙特阿拉伯最常见的癌症。然而,详细的已发表流行病学数据却很匮乏。在本研究中,对一家三级护理医院的乳腺癌患者进行了特征分析,并与来自美国的数据进行了比较。
对2004年至2011年间在萨阿德专科医院就诊的确诊为浸润性乳腺癌的女性患者的病历进行回顾性审查。计算描述性统计数据并与已发表的数据进行比较。
确定并分析了262例经细胞学或组织学确诊为浸润性乳腺癌的女性患者。与来自监测、流行病学和最终结果(SEER)数据库的已发表美国数据相比,患者确诊时年龄明显更小(<50岁:57.5% 对12.5%),且疾病分期更晚(局限性疾病:28.6% 对61.2%)。在我们的分析中,沙特阿拉伯和美国人口不同的年龄结构无法完全解释诊断年龄的差异。尽管总体乳房切除术率更高(58.2% 对38.5%),但按分期分析时,乳房切除术率未发现相关差异。
我们的数据表明,与美国相比,沙特阿拉伯这一地区的乳腺癌确诊时分期要高得多。需要在提高认识运动方面做出更多努力,使筛查和治疗更容易获得,以改善预后并降低目前相对较高的乳房切除术率。