Pelvic Floor Service, Department of General Surgery, University Hospital South Manchester NHS Trust, Wythenshawe Hospital, Southmoor Road, Manchester, United Kingdom.
Dis Colon Rectum. 2012 Feb;55(2):211-7. doi: 10.1097/DCR.0b013e31823b2499.
Anal acoustic reflectometry is a new reproducible technique that allows a viscoelastic assessment of anal canal function. Five new variables reflecting anal canal function are measured: the opening and closing pressure, opening and closing elastance, and hysteresis.
The aim of this study was to assess whether the parameters measured in anal acoustic reflectometry are clinically valid between continent and fecally incontinent subjects.
This was an age- and sex-matched study of continent and incontinent women.
The study was conducted at a university teaching hospital.
One hundred women (50 with fecal incontinence and 50 with normal bowel control) were included in the study. Subjects were age matched to within 5 years.
Parameters measured with anal acoustic reflectometry and manometry were compared between incontinent and continent groups using a paired t test. Diagnostic accuracy was assessed by the use of receiver operator characteristic curves.
Four of the 5 anal acoustic reflectometry parameters at rest were significantly different between continent and incontinent women (eg, opening pressure in fecally incontinent subjects was 31.6 vs 51.5 cm H2O in continent subjects, p = 0.0001). Both anal acoustic reflectometry parameters of squeeze opening pressure and squeeze opening elastance were significantly reduced in the incontinent women compared with continent women (50 vs 99.1 cm H2O, p = 0.0001 and 1.48 vs 1.83 cm H2O/mm, p = 0.012). In terms of diagnostic accuracy, opening pressure at rest measured by reflectometry was significantly superior in discriminating between continent and incontinent women in comparison with resting pressure measured with manometry (p = 0.009).
Anal acoustic reflectometry is a new, clinically valid technique in the assessment of continent and incontinent subjects. This technique, which assesses the response of the anal canal to distension and relaxation, provides a detailed viscoelastic assessment of anal canal function. This technique may not only aid the investigation of fecally incontinent subjects, but it may also improve our understanding of anal canal physiology during both the process of defecation and maintenance of continence.
分析声学反射仪是一种新的可重复使用的技术，它可以评估肛门管的粘弹性。有五个新的变量反映肛门管的功能：开口和关闭压力、开口和关闭弹性以及滞后。
本研究旨在评估分析声学反射仪测量的参数在有节制和无节制的受试者之间是否具有临床有效性。
这是一项对有节制和无节制的女性进行年龄和性别匹配的研究。
这项研究在一所大学教学医院进行。
共有 100 名女性（50 名患有粪便失禁，50 名具有正常的肠道控制）参与了这项研究。受试者的年龄相差不超过 5 岁。
使用分析声学反射仪和测压法测量的参数在失禁和节制组之间进行比较，采用配对 t 检验。通过使用接受者操作特征曲线评估诊断准确性。
在静止状态下，有节制和无节制的女性之间有 5 个分析声学反射仪参数中的 4 个有显著差异（例如，无节制的受试者的开口压力为 31.6cmH2O，而有节制的受试者的开口压力为 51.5cmH2O，p=0.0001）。在无节制的女性中，挤压开口压力和挤压开口弹性的两个分析声学反射仪参数均显著低于有节制的女性（50cmH2O 对 99.1cmH2O，p=0.0001 和 1.48cmH2O/mm 对 1.83cmH2O/mm，p=0.012）。就诊断准确性而言，与测压法测量的静息压力相比，反射仪测量的静息压力在区分有节制和无节制的女性方面具有显著优势（p=0.009）。
分析声学反射仪是一种新的、有临床有效性的评估有节制和无节制的受试者的技术。这种技术评估肛门管对膨胀和松弛的反应，提供了肛门管功能的详细粘弹性评估。这种技术不仅可以帮助调查粪便失禁的受试者，还可以提高我们对肛门管生理功能的理解，包括排便过程和维持节制能力。
