Department of Clinical Radiology, Leeds Teaching Hospitals, St James's University Hospital, Leeds, United Kingdom.
Clin Nucl Med. 2012 Feb;37(2):204-5. doi: 10.1097/RLU.0b013e31823ea1a5.
A 52-year-old female smoker presenting with unexplained weight loss underwent CT and FDG PET/CT imaging, which demonstrated an extremely hypermetabolic mediastinal mass with calcification, necrosis, and features of local invasiveness. Mediastinoscopy and biopsy were followed by successful surgical resection of an encapsulated mass showing the typical histologic features of follicular dendritic cell sarcoma (FDCS). FDCS of the mediastinum is a rare neoplasm arising from accessory cells of the immune system. Integrated FDG PET/CT of mediastinal FDCS highlights the importance of histologic assessment of mediastinal tumors that may seem unresectable on initial imaging.
一位 52 岁的女性吸烟者，出现不明原因的体重减轻，接受了 CT 和 FDG PET/CT 成像检查，结果显示纵隔内一个极度高代谢的肿块，伴有钙化、坏死和局部侵袭性特征。纵隔镜检查和活检后，成功切除了一个包裹性肿块，显示出滤泡树突状细胞肉瘤 (FDCS) 的典型组织学特征。纵隔 FDCS 是一种罕见的肿瘤，起源于免疫系统的辅助细胞。FDCS 的 FDG PET/CT 有助于强调对纵隔肿瘤进行组织学评估的重要性，这些肿瘤在初始成像时可能看似无法切除。
