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早期卵巢癌的腹腔镜手术分期

Laparoscopic surgical staging of early ovarian cancer.

作者信息

Weber Sarah, McCann Christopher K, Boruta David M, Schorge John O, Growdon Whitfield B

机构信息

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

出版信息

Rev Obstet Gynecol. 2011;4(3-4):117-22.

Abstract

Since its advent in the early 1990s, laparoscopic surgical staging for early ovarian cancer has been explored as an option with the potential to offer women equivalent cancer control and survival as provided by laparotomy but with the clear benefits of minimally invasive surgery. A limited but expanding body of literature suggests aggressive surgical staging can be performed with equivalent tissue assessment compared with laparotomy. Given the lack of randomized, controlled trials, the risks and benefits of such a procedure remain ambiguous. This review summarizes the current body of literature regarding the role of laparoscopy in upfront surgical staging of ovarian cancer. This review presents the history, rationale, and established benefits and risks of utilizing this approach in women who present with malignancy that appears confined to the ovary. Although retrospective data confirm the feasibility, safety, and efficacy of laparoscopic staging of early ovarian cancer, more prospective data will be required to confirm equivalent survival in a patient population that has the potential to be cured.

摘要

自20世纪90年代初问世以来,腹腔镜手术用于早期卵巢癌分期已被探索作为一种选择,它有可能为女性提供与开腹手术相当的癌症控制和生存率,但具有微创手术的明显优势。尽管文献数量有限且在不断增加,但表明与开腹手术相比,腹腔镜手术可以进行同样积极的手术分期及组织评估。由于缺乏随机对照试验,这种手术的风险和益处仍不明确。本综述总结了目前关于腹腔镜在卵巢癌初始手术分期中作用的文献。本综述介绍了在表现为局限于卵巢的恶性肿瘤的女性中使用这种方法的历史、基本原理以及既定的益处和风险。尽管回顾性数据证实了腹腔镜早期卵巢癌分期的可行性、安全性和有效性,但仍需要更多前瞻性数据来证实有可能治愈的患者群体中的生存率相当。

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