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获得性血管性水肿伴 C1 抑制剂缺乏与抗心磷脂抗体相关。

Acquired angioedema with C1 inhibitor deficiency associated with anticardiolipin antibodies.

出版信息

Int J Immunopathol Pharmacol. 2011 Oct-Dec;24(4):1115-8. doi: 10.1177/039463201102400433.

DOI:10.1177/039463201102400433
PMID:22230421
Abstract

Acquired angioedema (AAE) with C1 inhibitor deficiency is often associated to B cell lymphoproliferative disorders or autoimmune diseases. We report a case of AAE associated with IgM anti-cardiolipin antibodies, with frequent edematous attacks, that disappeared completely after a slight immunosuppression and danazol therapy.

摘要

获得性血管性水肿(AAE)伴 C1 抑制剂缺乏症常与 B 细胞淋巴增殖性疾病或自身免疫性疾病相关。我们报告了一例与 IgM 抗心磷脂抗体相关的 AAE 病例,该病例常发生水肿性发作,在轻微免疫抑制和达那唑治疗后完全消失。

相似文献

1
Acquired angioedema with C1 inhibitor deficiency associated with anticardiolipin antibodies.获得性血管性水肿伴 C1 抑制剂缺乏与抗心磷脂抗体相关。
Int J Immunopathol Pharmacol. 2011 Oct-Dec;24(4):1115-8. doi: 10.1177/039463201102400433.
2
Autoimmune acquired form of angioedema that responded to danazol therapy.对达那唑治疗有反应的自身免疫性获得性血管性水肿。
Intern Med. 2002 May;41(5):398-402. doi: 10.2169/internalmedicine.41.398.
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Autoimmune C1 inhibitor deficiency: report of eight patients.自身免疫性C1抑制物缺乏症:8例患者报告
Am J Med. 1993 Aug;95(2):169-75. doi: 10.1016/0002-9343(93)90257-p.
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The Janus faces of acquired angioedema: C1-inhibitor deficiency, lymphoproliferation and autoimmunity.获得性血管性水肿的双面性:C1抑制物缺乏、淋巴细胞增殖与自身免疫。
Clin Chem Lab Med. 2016 Feb;54(2):207-14. doi: 10.1515/cclm-2015-0195.
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[Immunocytoma with acquired C1-esterase inhibitor deficiency and recurrent angioneurotic edema].[伴有获得性C1酯酶抑制剂缺乏及复发性血管性水肿的免疫细胞瘤]
Dtsch Med Wochenschr. 1986 May 9;111(19):742-4. doi: 10.1055/s-2008-1068524.
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[Angioedema caused by C1 esterase inhibitor deficiency].[C1酯酶抑制剂缺乏所致血管性水肿]
Dtsch Med Wochenschr. 1998 Jun 5;123(23):737-40. doi: 10.1055/s-2007-1024047.
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Lymphoma-associated paraneoplastic angioedema with normal C1-inhibitor activity: does danazol work?伴有正常C1抑制物活性的淋巴瘤相关副肿瘤性血管性水肿:达那唑是否有效?
Am J Hematol. 2004 Nov;77(3):296-8. doi: 10.1002/ajh.20195.
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[Acquired C1 inhibitor deficiency associated with lymphoproliferative disorders: four cases].[与淋巴增殖性疾病相关的获得性C1抑制剂缺乏症:4例]
Rev Med Interne. 2004 Sep;25(9):667-72. doi: 10.1016/j.revmed.2004.06.003.
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Acquired C1-inhibitor deficiency.获得性C1抑制物缺乏症。
Behring Inst Mitt. 1989 Jul(84):161-4.
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[Acquired angioedema with C1-INH deficiency and accompanying chronic spontaneous urticaria in a patient with chronic lymphatic B cell leukemia].[一名慢性B淋巴细胞白血病患者伴C1-INH缺乏的获得性血管性水肿及慢性自发性荨麻疹]
Hautarzt. 2015 Oct;66(10):723-5. doi: 10.1007/s00105-015-3679-9.

引用本文的文献

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Serum complexes between C1INH and C1INH autoantibodies for the diagnosis of acquired angioedema.用于诊断获得性血管性水肿的 C1INH 与 C1INH 自身抗体的血清复合物。
Clin Exp Immunol. 2019 Dec;198(3):341-350. doi: 10.1111/cei.13361. Epub 2019 Sep 17.
2
Case report presenting the diagnostic challenges in a patient with recurrent acquired angioedema, antiphospholipid antibodies and undetectable C2 levels.病例报告:一名复发性获得性血管性水肿、抗磷脂抗体阳性且C2水平检测不到的患者所面临的诊断挑战。
Allergy Asthma Clin Immunol. 2018 Jun 4;14:24. doi: 10.1186/s13223-018-0246-9. eCollection 2018.