Department of Animal Medicine and Surgery, Equine Sport Medicine Center, CEMEDE, School of Veterinary Medicine, University of Córdoba, Spain.
Res Vet Sci. 2012 Oct;93(2):943-9. doi: 10.1016/j.rvsc.2011.11.009. Epub 2012 Jan 9.
In order to assess which laboratorial parameters need specific age- and/or gender-related reference values, hematological and biochemical profiles (including hormones) were performed in 205 Spanish foals of 5 groups: A (1-2 months; 20 fillies, 10 colts), B (2-3 months; 24 fillies, 18 colts), C (3-6 months; 25 fillies, 16 colts), D (6-9 months; 20 fillies, 23 colts) and E (9-12 months; 25 fillies, 15 colts). Additionally, 120 adult horses were sampled in order to establish baseline data for this breed in our laboratory. Group E had lower red blood cell number and mean cell volume than B, C and D, and neutrophil count was lower in A. Albumin was lower in A than in D, lactate was higher in B, C and D, CK, AST and K were higher in C. In D and E, cortisol was lower and adrenaline was higher. Urea progressively increases, whereas ALP decreases with age. Packed cell volume was higher in fillies of group A, creatinine was higher in colts of group E and fillies of groups B, C, and D had higher aldosterone than colts. In comparison to Spanish adult horses, mean cell volume, albumin, urea, CK, AST, LDH, and ALP requires specific ranges for foals.
为了评估哪些实验室参数需要特定的年龄和/或性别相关的参考值,对 205 匹西班牙小马的血液学和生化学特征(包括激素)进行了检测,这些小马分为 5 组:A(1-2 个月;20 匹母马,10 匹公马)、B(2-3 个月;24 匹母马,18 匹公马)、C(3-6 个月;25 匹母马,16 匹公马)、D(6-9 个月;20 匹母马,23 匹公马)和 E(9-12 个月;25 匹母马,15 匹公马)。此外,还对 120 匹成年马进行了采样,以便为我们实验室建立该品种的基线数据。E 组的红细胞数和平均红细胞体积低于 B、C 和 D 组,中性粒细胞计数低于 A 组。A 组的白蛋白低于 D 组,B、C 和 D 组的乳酸水平较高,C 组的 CK、AST 和 K 较高。D 和 E 组的皮质醇较低,肾上腺素较高。随着年龄的增长,尿素逐渐增加,而碱性磷酸酶则降低。A 组母马的红细胞压积较高,E 组公马的肌酐较高,B、C 和 D 组的母马的醛固酮高于公马。与西班牙成年马相比,平均红细胞体积、白蛋白、尿素、CK、AST、LDH 和 ALP 需要针对小马的特定范围。