帕金森病中惊恐障碍的家族聚集性。
Familial aggregation of panic disturbances in Parkinson's disease.
机构信息
Department of Psychiatry and Behavioral Sciences, Bloomberg School of Public Health, Baltimore, MD, USA.
出版信息
J Neuropsychiatry Clin Neurosci. 2011 Fall;23(4):417-24. doi: 10.1176/jnp.23.4.jnp417.
Panic disorder has an elevated prevalence in Parkinson's disease (PD). To explore the basis for this co-occurrence, the familial aggregation of panic disorder was examined in patients with PD. Probands and relatives of patients with PD and panic disorder (PD-PANIC; N=20, N=115) and control probands with PD and no active psychiatric illness (PD-NA; N=17, N=108) were interviewed by phone, using a structured interview to determine panic status. Lifetime prevalence of panic and "panic-like" disorders was higher in PD-PANIC than in PD-NA relatives. Panic and "panic-like" disorders are familial disorders in PD.
惊恐障碍在帕金森病（PD）中的患病率较高。为了探究这种共病发生的基础，研究人员对 PD 患者中的惊恐障碍家族聚集情况进行了研究。通过电话对 PD 伴惊恐障碍（PD-PANIC；N=20，N=115）和 PD 无活动性精神疾病（PD-NA；N=17，N=108）患者及其亲属进行了访谈，使用结构化访谈来确定惊恐障碍的状态。PD-PANIC 患者的惊恐障碍和“惊恐样”障碍终生患病率高于 PD-NA 亲属。惊恐障碍和“惊恐样”障碍是 PD 中的家族性疾病。
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