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植酸钠和葡萄糖酸钙浓度对钙离子渗透和肠道吸收的影响。

Influence of phosvitin and calcium gluconate concentration on permeation and intestinal absorption of calcium ions.

机构信息

Biochefa Pharmaceutical Research and Production Plant, Sosnowiec, Poland.

出版信息

Biol Trace Elem Res. 2012 Jun;147(1-3):374-7. doi: 10.1007/s12011-011-9298-0. Epub 2012 Jan 10.

Abstract

The effect of egg yolk phosvitin on the permeation and absorption of calcium was investigated in vitro in relation to calcium gluconate concentration. Obtained results indicate that phosvitin significantly reduces the intestinal calcium absorption from 1 and 10 mM of calcium gluconate solution. It is associated with the formation of the complex of Ca (II) ions with phosvitin. The process of calcium permeation increases under phosvitin influence when calcium gluconate concentrations rise up to 10 mM. At a higher concentration of calcium gluconate (20 mM), no effect of phosvitin was seen on permeation of calcium ions.

摘要

研究了蛋黄卵黄磷蛋白(phosvitin)对葡萄糖酸钙浓度相关的体外钙渗透和吸收的影响。结果表明,卵黄磷蛋白显著降低了 1mM 和 10mM 葡萄糖酸钙溶液中肠道对钙的吸收。这与 Ca(II)离子与卵黄磷蛋白形成复合物有关。当葡萄糖酸钙浓度上升至 10mM 时,卵黄磷蛋白的存在会增加钙渗透过程。在更高浓度的葡萄糖酸钙(20mM)下,卵黄磷蛋白对钙离子的渗透没有影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0287/3362700/ff6d27bbbab4/12011_2011_9298_Fig1_HTML.jpg

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本文引用的文献

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A model for calcium permeation into small intestine.
Biol Trace Elem Res. 2011 Sep;142(3):456-64. doi: 10.1007/s12011-010-8827-6. Epub 2010 Sep 1.
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