Mazeron Renaud, Khodari Wassim, Gilmore Jennifer, Champoudry Jérôme, Dumas Isabelle, Morice Philippe, Lhommé Catherine, Haie-Méder Christine
Institut de cancérologie Gustave-Roussy, Villejuif Cedex, France.
Bull Cancer. 2012 Jan;99(1):69-77. doi: 10.1684/bdc.2011.1519.
Several randomized studies published in recent years have greatly changed the management of postoperative endometrial cancer, especially for lesions of intermediate prognosis. Vaginal brachytherapy is now standard treatment for these lesions at the expense of external beam radiation, which, despite an improvement in locoregional control, has no impact on overall survival. This review aims to take stock of new indications for vaginal brachytherapy detailing the trials that led to change standards or care.
近年来发表的几项随机研究极大地改变了子宫内膜癌术后的治疗管理，尤其是对于预后中等的病变。阴道近距离放射治疗现已成为这些病变的标准治疗方法，而放弃了外照射放疗，尽管外照射放疗在局部区域控制方面有所改善，但对总生存期没有影响。本综述旨在评估阴道近距离放射治疗的新适应症，详细介绍导致治疗标准改变的试验。
