Novak Srdan
Odjel za reumatologiju i klinicku imunologiju, Klinika za internu medicinu, Klinicki bolnicki centar Rijeka, Kresimirova 42, 51000 Rijeka.
Reumatizam. 2011;58(2):47-50.
The most frequent early symptoms of spondyloarthritides are inflammatory back pain and asymetric peripheral arthritis. Currently the mean delay between the onset of first symptoms and diagnosing ankylosing spondylitis which is the frequent type of spondyloarthritis is over 5 years. The availability of effective therapies makes an early diagnosis mandatory. The clinical symptoms of inflammatory back pain, active inflamation on MR, and positivity for HLA-B27 are the most important parameters for an early diagnosis of spondyloarthritis, especially in combination. Moreover, the combination of clinical and laboratory parameters is necessary for the early diagnosis.
脊柱关节炎最常见的早期症状是炎性背痛和不对称性外周关节炎。目前,从首次出现症状到诊断出强直性脊柱炎(脊柱关节炎最常见的类型)之间的平均延误时间超过5年。有效治疗方法的出现使得早期诊断成为必需。炎性背痛的临床症状、磁共振成像(MR)上的活动性炎症以及HLA - B27阳性是脊柱关节炎早期诊断最重要的参数,尤其是联合起来时。此外,临床和实验室参数的联合对于早期诊断是必要的。