Morgan J M, Oldershaw P J, Gray H H
Department of Cardiology, Brompton Hospital, London.
Br Heart J. 1990 Oct;64(4):261-5. doi: 10.1136/hrt.64.4.261.
Before the introduction of computed tomographic (CT) scanning, aortography was the investigation of choice for acute aortic dissection. Between 1978 and 1982, 24 patients were referred to the Brompton Hospital with suspected acute thoracic aortic dissection; all had aortography with diagnosis confirmed at surgery (n = 12) or necropsy (n = 2) or supported by clinical outcome (n = 8). One patient in whom aortography was negative had type B dissection at necropsy and another patient was lost to follow up. CT scanning became available in this unit in 1983 and between 1983 and 1987 was used as the only imaging investigation in 32 patients with suspected acute dissection of the thoracic aorta while in a further 22 patients aortography was used alone. Results were confirmed at surgery (n = 18), necropsy (n = 3), or supported by clinical outcome (n = 31). Two patients were lost to follow up. In an additional 16 patients both aortography and CT scanning were performed with concordant findings in 10. In six in whom the results were discordant, aortography was normal in three in whom subsequent CT scanning showed type B dissection and CT scanning was normal in three patients in whom aortography showed type A dissection. Both CT scanning and aortography are reliable techniques for assessment of suspected acute dissection of the thoracic aorta. Both techniques misdiagnose occasionally and the frequency of misdiagnosis will be minimised by performing both investigations in patients where the level of clinical suspicion is high and the initial investigation negative. CT scanning tends to miss type A dissection and in view of the success of surgery in this condition this failing has the more serious clinical consequences.
在计算机断层扫描(CT)引入之前,主动脉造影是急性主动脉夹层的首选检查方法。1978年至1982年间,有24例疑似急性胸主动脉夹层的患者被转诊至布朗普顿医院;所有患者均接受了主动脉造影,其中12例在手术中确诊,2例在尸检中确诊,8例通过临床结果得到证实。1例主动脉造影结果为阴性的患者在尸检时发现为B型夹层,另1例患者失访。该科室于1983年开始使用CT扫描,1983年至1987年间,32例疑似急性胸主动脉夹层的患者仅接受了CT扫描作为唯一的影像学检查,另有22例患者仅接受了主动脉造影。结果在手术中得到证实(18例)、尸检中得到证实(3例)或通过临床结果得到支持(31例)。2例患者失访。另外16例患者同时进行了主动脉造影和CT扫描,其中10例结果一致。在6例结果不一致的患者中,3例主动脉造影正常,随后的CT扫描显示为B型夹层,3例CT扫描正常,而主动脉造影显示为A型夹层。CT扫描和主动脉造影都是评估疑似急性胸主动脉夹层的可靠技术。两种技术偶尔都会出现误诊,对于临床怀疑程度高且初始检查结果为阴性的患者,同时进行两项检查可将误诊频率降至最低。CT扫描往往会漏诊A型夹层,鉴于这种情况下手术的成功率,这种漏诊具有更严重的临床后果。