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使用茴香酰化纤溶酶原链激酶激活剂复合物治疗后出现皮疹。

Rash after treatment with anistreplase.

作者信息

Burrows N, Jones R R

机构信息

Department of Dermatology, Ealing Hospital, Southall, Middlesex.

出版信息

Br Heart J. 1990 Oct;64(4):289-90. doi: 10.1136/hrt.64.4.289.

DOI:10.1136/hrt.64.4.289
PMID:2223309
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1024424/
Abstract

A palpable purpura developed on the legs and lower abdomen of a woman of 54 five days after she was treated with anistreplase anisoylated plasminogen streptokinase activator complex (APSAC) for an acute myocardial infarction. Histological examination of a skin biopsy specimen taken 6 days after treatment showed leucocytoclastic vasculitis. The rash resolved within two weeks and there were no other complications.

摘要

一名54岁女性在接受茴香酰化纤溶酶原链激酶激活剂复合物(APSAC)治疗急性心肌梗死后五天,其腿部和下腹部出现了可触及的紫癜。治疗六天后获取的皮肤活检标本的组织学检查显示为白细胞破碎性血管炎。皮疹在两周内消退,且无其他并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1863/1024424/3063c6f66f34/brheartj00058-0059-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1863/1024424/3063c6f66f34/brheartj00058-0059-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1863/1024424/3063c6f66f34/brheartj00058-0059-a.jpg

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1
Rash after treatment with anistreplase.使用茴香酰化纤溶酶原链激酶激活剂复合物治疗后出现皮疹。
Br Heart J. 1990 Oct;64(4):289-90. doi: 10.1136/hrt.64.4.289.
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本文引用的文献

1
Serum sickness following streptokinase therapy.链激酶治疗后的血清病
AJR Am J Roentgenol. 1982 Jan;138(1):143-4. doi: 10.2214/ajr.138.1.143.
2
Serum sickness complicating intravenous streptokinase therapy in acute myocardial infarction.急性心肌梗死静脉注射链激酶治疗并发血清病
Eur Heart J. 1984 Dec;5(12):1010-2. doi: 10.1093/oxfordjournals.eurheartj.a061602.
3
Serum sickness-like illness and leukocytoclastic vasculitis following intracoronary arterial streptokinase.冠状动脉内注射链激酶后发生的血清病样疾病和白细胞破碎性血管炎。
Am Heart J. 1987 Feb;113(2 Pt 1):395-7. doi: 10.1016/0002-8703(87)90287-0.
4
Vasculitis complicating treatment with intravenous anisoylated plasminogen streptokinase activator complex in acute myocardial infarction.急性心肌梗死患者静脉注射茴香酰化纤溶酶原链激酶激活剂复合物治疗并发血管炎
Br Heart J. 1988 Jan;59(1):9-11. doi: 10.1136/hrt.59.1.9.