Bayram Mehmet, Babalık Mesiha, Bakan Nur Dilek, Döngel Isa
Clinic of Chest Diseases, Sivas Numune Training and Research Hospital, Sivas, Turkey.
Tuberk Toraks. 2011;59(4):380-3. doi: 10.5578/tt.1159.
Burkholderia cepacia is a gram-negative bacilli leading to pneumonia with poor prognosis and usually seen in patients with immunosuppression or with structural lung diseases. This report is about two patients with no underlying disease diagnosed as B. cepacia pneumonia mimicking malignancy and tuberculosis. Bronchoscopy was applied on both patients since no response to treatment with wide spectrum antibiotics and negative sputum smears for acid-fast bacili. B. cepacia was isolated from bronchial lavage culture. Antibiogram revealed sensitivity to quinolones in both cases. Radiological and clinical complete remission was seen in patients by quinolones. The current cases showed that community-acquired Burkholderia pneumonia is possible in healthy patients. Bronchial washing is important in diagnosis.
洋葱伯克霍尔德菌是一种革兰氏阴性杆菌，可导致预后不良的肺炎，常见于免疫抑制患者或患有结构性肺病的患者。本报告讲述的是两名无基础疾病的患者，他们被诊断为洋葱伯克霍尔德菌肺炎，临床表现类似恶性肿瘤和肺结核。由于广谱抗生素治疗无效且痰涂片抗酸杆菌阴性，两名患者均接受了支气管镜检查。从支气管灌洗培养物中分离出了洋葱伯克霍尔德菌。药敏试验显示两例患者对喹诺酮类药物敏感。使用喹诺酮类药物后，患者的影像学和临床症状完全缓解。目前的病例表明，健康患者也有可能发生社区获得性洋葱伯克霍尔德菌肺炎。支气管灌洗在诊断中很重要。
