Oida Takatsugu, Mimatsu Kenji, Kano Hisao, Kawasaki Atsushi, Kuboi Youichi, Fukino Nobutada, Kida Kazutoshi, Amano Sadao
Department of Surgery, Yokohama Central Hoapital, Yokohama, Japan.
Hepatogastroenterology. 2011 Nov-Dec;58(112):1985-8. doi: 10.5754/hge09484.
BACKGROUND/AIMS: Esophageal stenting with self-expandable metallic stents can effectively relieve malignant esophageal strictures in patients in whom chemoradiotherapy has failed. However, airway stenosis can sometimes occur after esophageal stenting. This study aims to evaluate the efficacy of double stents (combined esophageal and airway stents) in patients with recurrent and unresectable esophageal carcinoma in whom definitive chemoradiotherapy has failed.
We retrospectively studied 35 patients who underwent esophageal stenting for recurrent esophageal carcinoma after failure of chemoradiotherapy. These patients were divided into 2 groups; the E group, consisting of patients who underwent esophageal stenting alone and the D group, consisting of patients who required airway stenting after esophageal stenting due to airway compression. Bronchoscopy was performed before esophageal stenting in all patients.
In all 5 patients developed airway stenosis after esophageal stenting. With regard to the bronchoscopic findings before esophageal stenting, the incidence of category-2b findings was significantly higher in the D group than in the E group. Mean survival was 60 days (range 24-102 days).
Accurate bronchoscopic examination with special attention to compression of the airway should be performed before esophageal stenting in patients in whom the bronchoscopic findings are classified as category 2b or higher.
背景/目的:自膨式金属支架置入术可有效缓解放化疗失败患者的恶性食管狭窄。然而,食管支架置入术后有时会发生气道狭窄。本研究旨在评估双支架(食管和气道联合支架)对放化疗失败的复发性、不可切除食管癌患者的疗效。
我们回顾性研究了35例放化疗失败后因复发性食管癌接受食管支架置入术的患者。这些患者被分为两组;E组为仅接受食管支架置入术的患者,D组为食管支架置入术后因气道受压需要气道支架置入的患者。所有患者在食管支架置入术前均进行了支气管镜检查。
所有患者中有5例在食管支架置入术后发生气道狭窄。关于食管支架置入术前的支气管镜检查结果,D组2b类结果的发生率显著高于E组。平均生存期为60天(范围24 - 102天)。
对于支气管镜检查结果分类为2b类或更高的患者,在食管支架置入术前应进行准确的支气管镜检查,并特别注意气道受压情况。