Department of Neurosurgery, G B Pant Hospital, New Delhi, India.
Neurol India. 2011 Nov-Dec;59(6):867-73. doi: 10.4103/0028-3886.91367.
Endoscopic third ventriculostomy (ETV) has replaced shunt surgery for several indications. Failure of ETV secondary to restenosis can result in recurrence of symptoms of raised intracranial pressure.
To analyze the rates of restenosis due to ostomy closure and factors resulting in failures and to assess the role of re-ETV in such cases.
Re-ETV was performed after counselling and obtaining informed consent. The technique of re-ETV was essentially the same as in primary ETV. Video analysis of primary ETV was performed before selecting a patient for re-ETV. Factors analyzed included age, gender, etiology of hydrocephalus, cerebrospinal fluid (CSF) findings, presence of shunt tube and adequacy of ETV and bleeding at the time of ETV.
Thirty-two patients underwent re-ETV. The mean interval between the first ETV and re-ETV was 1.4 years (3 days to 2.9 years). Overall failure of ETV due to restenosis was 8.78%. The technical success rate of performing re-ETV was 93.2%. The overall clinical recovery following surgery was observed in 89% of the patients, three from early and 25 from delayed ETV failures. The radiological recovery was seen in 20 (63%) patients. The good flow of CSF via the re-ETV site was documented with cine mode magnetic resonance imaging (MRI) in seven patients. Unlike primary ETV, the success of re-ETV in children aged less than 2 years was 90% (P < 0.005). There were 56.25% failure of ETV in patients with previous infection or foreign body within the ventricle (P < 0.001). While the chances of restenosis were high in the procedure with some infections, the outcome was equally better. Gender of the patients and CSF findings had no influence on ostomy closure.
re-ETV can be considered in carefully selected patients of failed ETV. It is more useful in delayed ETV failures and can be offered before a patient is advised VP shunt.
内镜第三脑室造瘘术(ETV)已取代分流手术用于多种适应证。由于再狭窄导致 ETV 失败可导致颅内压升高症状复发。
分析由于造口关闭导致再狭窄的发生率和导致失败的因素,并评估在这种情况下再次 ETV 的作用。
在咨询并获得知情同意后进行再次 ETV。再次 ETV 的技术与初次 ETV 基本相同。在选择患者进行再次 ETV 之前,对初次 ETV 的视频进行分析。分析的因素包括年龄、性别、脑积水的病因、脑脊液(CSF)发现、分流管的存在以及初次 ETV 时的 ETV 充分性和出血情况。
32 例患者接受了再次 ETV。首次 ETV 和再次 ETV 之间的平均间隔为 1.4 年(3 天至 2.9 年)。由于再狭窄导致 ETV 整体失败的发生率为 8.78%。再次 ETV 的技术成功率为 93.2%。术后总体临床恢复率为 89%,3 例为早期 ETV 失败,25 例为延迟 ETV 失败。20 例(63%)患者影像学恢复。7 例患者通过电影模式磁共振成像(MRI)记录到再 ETV 部位 CSF 流量良好。与初次 ETV 不同,年龄小于 2 岁的患者再次 ETV 成功率为 90%(P < 0.005)。脑室有既往感染或异物的患者 ETV 失败率为 56.25%(P < 0.001)。虽然在有一些感染的情况下,再狭窄的可能性很高,但结果同样更好。患者的性别和 CSF 发现对造口关闭没有影响。
对于 ETV 失败的患者,可以考虑进行再次 ETV。对于延迟性 ETV 失败更有用,可以在建议患者接受脑室-心房分流术之前提供。