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多发婴儿性肝血管瘤——普萘洛尔和类固醇治疗后的影像学策略和反应,包括文献复习。

Multifocal infantile hepatic hemangiomas--imaging strategy and response to treatment after propranolol and steroids including review of the literature.

机构信息

Division of Pediatric Radiology, Department of Radiology and Radiological Science, Johns Hopkins Hospital, 600 North Wolfe Street, Nelson Basement, B-172, Baltimore, MD 21287-0842, USA.

出版信息

Eur J Pediatr. 2012 Jul;171(7):1023-8. doi: 10.1007/s00431-011-1671-7. Epub 2012 Jan 11.

Abstract

Infantile hepatic hemangioma is the most common benign liver tumor during infancy. Prompt diagnosis and timely institution of therapy are of utmost importance. Magnetic resonance imaging (MRI) plays a key role in the correct diagnosis and monitoring of treatment. We report on a 15-week-old girl with multifocal infantile hemangiomas of the liver and high output congestive heart failure. Diagnosis was confirmed by MRI. Subsequent treatment with propranolol and steroids showed dramatic regression of the lesions within 24 weeks. We present the characteristic MRI findings and discuss treatment options together with a comprehensive review of the relevant literature. Conclusion Propranolol appears highly efficacious in the management of infantile hepatic hemangioma; dedicated MRI is essential in confirming the diagnosis and monitoring of treatment.

摘要

婴儿肝脏血管瘤是婴儿期最常见的良性肝脏肿瘤。及时准确的诊断和及时的治疗至关重要。磁共振成像(MRI)在正确诊断和监测治疗方面发挥着关键作用。我们报告了一例 15 周大的女孩,患有肝多灶性婴儿血管瘤和高输出充血性心力衰竭。通过 MRI 确诊。随后使用普萘洛尔和类固醇治疗,24 周内病变明显消退。我们呈现了特征性的 MRI 发现,并结合相关文献的全面回顾讨论了治疗选择。结论普萘洛尔在婴儿肝脏血管瘤的治疗中具有高度疗效;专用 MRI 对于确认诊断和监测治疗至关重要。

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