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巴勒斯坦药学实践中药物调配的决定因素及频率

Determinants and frequency of pharmaceutical compounding in pharmacy practice in Palestine.

作者信息

Zaid Abdel Naser, Al-Ramahi Rowa', Shahed Qusai, Saleh Belal, Elaraj Josephean

机构信息

Department of Pharmaceutics and Pharmacokinetics, An-Najah National University, Nablus, Palestine.

出版信息

Int J Pharm Pract. 2012 Feb;20(1):9-14. doi: 10.1111/j.2042-7174.2011.00157.x. Epub 2011 Aug 19.

DOI:10.1111/j.2042-7174.2011.00157.x
PMID:22236175
Abstract

OBJECTIVES

The aims of this study were to determine the frequency of prescription compounding by community pharmacists, identify factors that influence pharmacists' decisions to provide compounding services, and evaluate physicians' perspectives on prescribing medications that require compounding.

METHODS

The study was a cross-sectional survey administered via face-to-face structured interviews with randomly selected community pharmacists and physicians from different areas of the West Bank.

KEY FINDINGS

Of the 260 community pharmacists who were contacted, 212 agreed to participate in the survey, giving a response rate of 81.5%. Overall, 153 (72.2%) of respondent pharmacists provided compounding services. Compounded prescriptions accounted for 1973 (1.55%) of 126,840 prescriptions dispensed in a typical month. Among the compounders, 112 (73.2%) pharmacists reported that their goal in providing full pharmaceutical care to their patients was the most important motivator. The most frequently reported reason for not providing compounding was 'I do not receive prescriptions that require compounding' by 43 out of 59 (72.9%) pharmacists. A total of 179 out of 220 physicians consented to participate in this study giving a response rate of 81.4%. The majority of physicians (142, 79.3%) did not prescribe compounded medicines. The most important reason for their decision to prescribe compounded medicines was the unavailability of the required dosage forms. The most commonly cited reason for not prescribing them was a lack of trust in the quality of the compounded formulations.

CONCLUSION

While most respondent pharmacists provide a compounding service this represents only a small percentage of the total volume of dispensed prescriptions. Most responding physicians do not prescribe medications that require compounding because they lack trust in the quality of the compounded formulations.

摘要

目的

本研究旨在确定社区药剂师进行处方调配的频率,识别影响药剂师提供调配服务决策的因素,并评估医生对开具需要调配的药物的看法。

方法

该研究是一项横断面调查,通过对从约旦河西岸不同地区随机选取的社区药剂师和医生进行面对面的结构化访谈来实施。

主要发现

在联系的260名社区药剂师中,212名同意参与调查,回复率为81.5%。总体而言,153名(72.2%)受访药剂师提供调配服务。在一个典型月份分发的126,840张处方中,调配处方占1973张(1.55%)。在提供调配服务的药剂师中,112名(73.2%)报告称,他们为患者提供全面药学服务的目标是最重要的动机。59名药剂师中有43名(72.9%)报告称,不提供调配服务的最常见原因是“我没有收到需要调配的处方”。220名医生中有179名同意参与本研究,回复率为81.4%。大多数医生(142名,79.3%)不开具调配药物。他们决定开具调配药物的最重要原因是所需剂型无法获得。不开具调配药物最常提到的原因是对调配制剂质量缺乏信任。

结论

虽然大多数受访药剂师提供调配服务,但这仅占总处方量的一小部分。大多数受访医生不开具需要调配的药物,因为他们对调配制剂的质量缺乏信任。

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