一项关于巴勒斯坦医院纳米药物可用性及药剂师相关知识的横断面研究。
A cross-sectional study of the availability and pharmacist's knowledge of nano-pharmaceutical drugs in Palestinian hospitals.
作者信息
Assali Mohyeddin, Shakaa Ali, Abu-Hejleh Sabaa, Abu-Omar Reham, Karajeh Nareman, Ajory Nawal, Zyoud Saed, Sweileh Waleed
机构信息
Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
出版信息
BMC Health Serv Res. 2018 Apr 5;18(1):250. doi: 10.1186/s12913-018-3060-7.
BACKGROUND
Nanomedicine is the medical application of nanomaterials that may have an infinite size with the range less than 100 nm. This science has provided solutions to many of the current limitations in the diagnosis and treatment of diseases. Therefore, the pharmacist's knowledge and awareness of nano-pharmaceutical drugs will increase their availability in the market, and will improve the patient's compliance to their drug therapy. This study aimed to determine the availability of nano-pharmaceutical drugs in Palestinian hospitals and evaluate the extent of pharmacist's knowledge about them.
METHODS
A cross-sectional study design questionnaire was used to determine the availability of nano-pharmaceutical drugs based on the database of the ministry of health in the Palestinian hospitals (governmental, private and non- governmental organizations). Moreover, the knowledge of these nano-pharmaceutical drugs among pharmacists working in Palestinian hospitals was assessed based on developed questionnaire from the literature of the pharmaceutical formulations and nano-formulations. The variables were analyzed using Statistical Package for Social Sciences (SPSS 22).
RESULT
Fifty six pharmacists from 27 hospitals in the West bank completed the survey. The results regarding the availability of nano-pharmaceutical drugs indicated only eight available in hospitals with a frequency range 0-39.3%. Moreover, pharmacist's knowledge in the pharmaceutical formulations was better than that in nano-formulations.
CONCLUSIONS
The availability of nano-pharmaceutical drugs in Palestinian hospitals was not adequate due to the lack of various nano-pharmaceutical drugs. The knowledge among pharmacists regarding nano-pharmaceutical drugs should be improved by providing courses in nanomedicine during the undergraduate pharmacy programs.
背景
纳米医学是纳米材料在医学上的应用，这些纳米材料的尺寸范围可能小于100纳米且大小不一。这门科学为当前疾病诊断和治疗中的许多局限性提供了解决方案。因此，药剂师对纳米药物的了解和认识将提高其在市场上的可及性，并提高患者对药物治疗的依从性。本研究旨在确定巴勒斯坦医院中纳米药物的可及性，并评估药剂师对它们的了解程度。
方法
采用横断面研究设计问卷，根据巴勒斯坦医院（政府、私立和非政府组织）卫生部的数据库确定纳米药物的可及性。此外，根据从药物制剂和纳米制剂文献中制定的问卷，评估在巴勒斯坦医院工作的药剂师对这些纳米药物的了解情况。使用社会科学统计软件包（SPSS 22）对变量进行分析。
结果
约旦河西岸27家医院的56名药剂师完成了调查。关于纳米药物可及性的结果表明，医院中仅有8种纳米药物可用，频率范围为0-39.3%。此外，药剂师对药物制剂的了解优于对纳米制剂的了解。
结论
由于缺乏各种纳米药物，巴勒斯坦医院中纳米药物的可及性不足。应通过在本科药学课程中提供纳米医学课程来提高药剂师对纳米药物的了解。
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