血管痉挛性蛛网膜下腔出血中的 copeptin。
Copeptin in aneurysmal subarachnoid hemorrhage.
机构信息
Department of Neurosurgery, Johns Hopkins University School of Medicine, The Johns Hopkins Hospital, 600 N, Wolfe Street, Meyer 8-181, Baltimore, MD 21287, USA.
出版信息
Crit Care. 2012 Jan 10;16(1):103. doi: 10.1186/cc10594.
Abstract
Copeptin is a peptide derived from pre-provasospression along with arginine vasospressin. In the setting of aneurysmal subarachnoid hemorrhage (SAH), elevated serum copeptin levels correlate with vasospasm, inpatient mortality, mortality at 1 year, and poor functional outcome at 1 year. The potential role of serum copeptin levels in the management of patients with aneurysmal SAH is promising and should be explored further.
摘要
copeptin 是一种从 pre-provasospression 与精氨酸血管加压素衍生而来的肽。在颅内动脉瘤性蛛网膜下腔出血（SAH）的情况下，血清 copeptin 水平升高与血管痉挛、住院死亡率、1 年死亡率以及 1 年时的不良功能结局相关。血清 copeptin 水平在颅内动脉瘤性 SAH 患者管理中的潜在作用很有前景，应进一步探讨。
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